A recent AIDES commercial for AIDS awareness shows a man’s IQ rapidly decreasing as he gets undressed. The entertaining clip features the Black Keys and RZA’s ‘The Baddest Man Alive.’

The song is the opening track on ‘The Man with the Iron Fists’ soundtrack, which was released last fall via Soul Temple Entertainment. The disc, which also features the likes of Kanye West, Pusha T and Corinne Bailey Rae, achieved rapid commercial success and landed at No. 31 on the Billboard 200 chart.

“There's tension within the songs, there is emotion and nuance in sound, a bit like a full-scale assault on one's imagination,” wrote the Huffington Post in a 2012 review. Rolling Stone called it a “a tasty mixtape – a blend of vintage R&B, neosoul and hip-hop.”

You may have heard a number of tunes by the Black Keys in various other TV spots, including trailers for ‘The Campaign,’ ‘Warm Bodies,’ ‘Deadliest Catch’ and ‘Sons of Anarchy,’ as well as commercials for Lexus, Audi, HSBC and a promo for last year’s NCAA March Madness.

The Ohio-based garage rockers have a series of North American tour dates lined up – check out their official site for the full itinerary.

Hear the Black Keys and RZA’s ‘The Baddest Man Alive’ in the AIDES 2013 Commercial